PRP

Autologous: no exogenous allergenic protein
A growth-factor cascade, not volume
Skin and hair indications are separate
The preparation protocol must be standardised

PRP (platelet-rich plasma) is venous blood centrifuged so a platelet concentrate can be returned to the same person’s dermis or scalp. Alpha granules release PDGF, TGF-β, VEGF, EGF and IGF-1; the aim is not volume but a controlled wound-healing cascade. PRF claims slower release from a fibrin matrix. Evidence is moderate for glow and as an adjunct in androgenetic alopecia; it does not replace ptosis, breast volume or baldness surgery. Preparation (single/double spin, leukocyte content) affects the result.

Personal consultation

Muscle, volume and skin quality are assessed together; product, dose and indication are planned individually.

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Safety and aftercare

Procedure at a glance

AnesthesiaTopical

Session time30–45 min

Sessions3–4 sessions, monthly

Persistence of resultsMaintenance 4–6 months

Return to workSame day

Recovery periodRedness 24–48 h

Concentrating platelets — not manufacturing miracle cells

Whole-blood platelet count varies by person. PRP is plasma separated from red cells in an anticoagulated tube, enriched to a multiple of baseline platelet density. Leukocyte-rich (L-PRP) preparations can raise inflammatory cytokine load; leukocyte-poor choices are debated on facial skin. ‘Stem cell’ marketing is wrong: PRP is not a mesenchymal stem-cell product. Growth factors stimulate angiogenesis, fibroblast migration and ECM synthesis; they do not occupy space like cross-linked HA. PRF (platelet-rich fibrin) is a fibrin network made without anticoagulant; release kinetics differ, and superiority is not proven in every indication.

01The same ‘PRP’ label is a different biological product at different rpm and kits
02Microneedling is a delivery method that increases the contact surface for growth factors

Aftercare timeline

Risks and Safety

01Bruise and tenderness at injection sites
02Temporary swelling or nodularity
03Infection (if the closed system is breached)
04Vasovagal reaction (venepuncture)
05Rare temporary telogen shock on the scalp
06Failure to achieve the expected response

The right indication, anatomical planning and careful technique reduce complication risk.

Procedures

01
Facial PRP
Intradermal injection or microneedling of the surface — fine line and glow, not malar projection.
02
Hair PRP
Adjunct to medical care in androgenetic alopecia and telogen effluvium; a limited role in scarring alopecia.
03
PRF
A fibrin matrix without anticoagulant and a claim of slower cytokine release. Indications overlap PRP; the protocol differs.

Frequently Asked Questions

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